Table 3. Fibril Primary Nucleation Rate, Critical Nucleation Rate, and Maximum Growth Rate, Elongation Rate, and Secondary Nucleation Rate for Crowder Volume Fractions ϕ = 0.00, 0.10, and 0.20 and Crowder Diameters 5, 20, and 40 Å and Total Crowder Surface Area Obtained by Fitting Simulation Data to Eqs 6–11.

	crowder size, crowder volume fraction, and total crowder surface area
		D = 40 Å	D = 40 Å	D = 20 Å	D = 20 Å	D = 5 Å	D = 5 Å
	no crowders	ϕ = 0.10	ϕ = 0.20	ϕ = 0.10	ϕ = 0.20	ϕ = 0.10	ϕ = 0.20
kinetic parameters	ϕ = 0.00	96 × 10–4 Å2	192 × 10–4 Å2	192 × 10–4 Å2	384 × 10–4 Å2	786 × 10–4 Å2	1536 × 10–4 Å2
kn (M–1 time–1)	0.21 ± 0.06	0.25 ± 0.10	0.24 ± 0.06	0.20 ± 0.09	0.25 ± 0.05	0.25 ± 0.09	0.46 ± 0.18
knc (M–1 time–1)	0.03 ± 0.01	0.04 ± 0.01	0.07 ± 0.01	0.07 ± 0.01	0.12 ± 0.02	0.15 ± 0.03	0.26 ± 0.02
rmax (peptides time–1)	0.05 ± 0.02	0.08 ± 0.02	0.13 ± 0.02	0.13 ± 0.02	0.24 ± 0.04	0.29 ± 0.05	0.51 ± 0.04
k+ (M–1 time–1)	1.40 ± 0.44	2.17 ± 0.35	3.31 ± 0.40	3.42 ± 0.43	5.85 ± 0.78	13.48 ± 2.94	11.38 ± 2.03
k2 (M–2 time–1)	1.45 ± 0.46	2.53 ± 0.66	4.03 ± 0.64	3.97 ± 0.64	7.41 ± 1.58	4.87 ± 4.55	17.53 ± 10.33