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. Author manuscript; available in PMC: 2015 Nov 7.
Published in final edited form as: Brain Res. 2014 Sep 16;1588:168–174. doi: 10.1016/j.brainres.2014.09.023

Figure 1. Progranulin is widely detected throughout the retina and is localized to the lysosome in cortical neurons Figure Legends.

Figure 1

(A) Immunohistochemistry was performed on mature wild-type retinas and expression was detected throughout the retina. (B) Immunohistochemistry was performed on adult Grn−/− retina. As expected, Grn−/− mice did not exhibit expression of Grn. The outer nuclear layer (ONL), inner nuclear layer (INL) are ganglion cell layer (GCL) are labeled. (C) Immunohistochemistry was performed on primary cortical neuronal cultures using anti-Lamp1 (green) and anti-Progranulin antibodies (red).