Table 2.

Description of the seven significant survival-associated loci identified in oral rinse samples during the Replication stage and their associated genes if applicable.

Locus ID	Chromosome	Located in a CpG Island	Located in an enhancer region	UCSC RefGene Group	Associated Gene	Associated Gene Descriptionb
cg02319972	15	No	Yes	[intergenic]
cg03784083	11	No	Yes	Body	OPCML	Opioid binding-cell adhesion molecule; highly conserved member of the IgLON subfamily of immunoglobulins; two transcript variants have been identified
cg15740054	19	Yes	No	5’UTR; TSS200	ADCK4	Uncharacterized AarF Domain Containing Kinase 4; unknown function, although it contains kinase domain; multiple transcript variants have been identified
cg18928362	14	No	No	TSS1500	ZFYVE26	Encodes a protein which contains a FYVE zinc finger binding domain; involved in cytokinesis; may have involvement in homologous recombination DNA double-strand break repair
cg21022792	6	No	No	Body	GABBR1	Gamma-Aminobutyric Acid B Receptor 1; receptor for a major inhibitory neurotransmitter (GABA); multiple splice variants have been identified
cg21702497	16	Yes	No	5’UTR	POLR3E	RNA polymerase III; catalyzes the transcription of DNA into RNA; involved with innate immune response
cg25914931	10	Yes	No	TSS200	KIF11	Kinase Family Member 11; involvement in spindle dynamics

Abbreviations: 5’UTR = 5’-untranslated region; TSS200 = within 200 bases of the transcription start site; TSS1500 = within 1500 bases of the transcription start site