Table 1.

Affinities for the tested substrates in this study compared to human and fish transporters of the Oatp1 family. Given as Km value in μM.

subtype	species	Km [μM]			references
		E3S	TCA	MTX
OATP1B1	Human	0.23/45	10–34	-	(Abe et al., 1999; Cui et al., 2001; Hsiang et al., 1999; Noé et al., 2007)
OATP1B3	Human	58	6–42	25–39	(Abe et al., 2001; Briz et al., 2006; Gui et al., 2008; Leuthold et al., 2009)
OATP1A2	Human	16–59	60	457	(Badagnani et al., 2006; Bossuyt et al., 1996; Kullak-Ublick et al., 1995; Lee et al., 2005)
Oatp1d1	Zebrafish	1.75	-	-	(Popovic et al., 2013)
Oatp1d1	Little skate	61	85	-	(Cai et al., 2002)
Oatp1d1	Rainbow trout	13.9	103	13.4