Table 1.
WT midgut | G30 midgut | |
---|---|---|
Kd (nM)a | 13.4 | 30.5 |
Binding affinity of WT and G30 was tested with early fourth-instar larvae midguts. Specific binding of biotin-labeled Cry11Aa to BBMV was obtained from total binding minus nonspecific binding. Cry11Aa binding affinity for G30 BBMV was slightly reduced. Kd values were obtained from the concentration corresponding to half the saturation response of specific binding.
The Kd values reported are the mean of three separate experiments.