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. Author manuscript; available in PMC: 2015 Nov 28.
Published in final edited form as: J Control Release. 2014 Sep 16;194:341–349. doi: 10.1016/j.jconrel.2014.09.006

Figure 4.

Figure 4

Effect of the number of mannose units per NC on NC uptake into J774.E cells. Cells were incubated with each of the five FITC-labeled NCs for 1 hr then sequentially washed. The cells were lysed with 1 N NaOH and neutralized with 1 N HCl. The fluorescence was measured and the readings were normalized by the amount of protein lysates. Data are reported as the mean +/− s.d. of three independent experiments. *: p < 0.05 = difference between the uptake level of the 2 unit mannose NC and that of a NC with a different mannose unit number. Control: non-mannosylated NC (n = 0).