Skip to main content
. Author manuscript; available in PMC: 2015 Nov 6.
Published in final edited form as: Cell Stem Cell. 2014 Oct 9;15(5):605–618. doi: 10.1016/j.stem.2014.09.008

Figure 3. Hepatocyte-derived oval cells are transcriptional distinct from bile ducts.

Figure 3

A) FACS separation of MIC1-1C3+ cells based on ROSA-mTomato resulted in 98.4-99.2% enrichment in mTomato+ cells relative to mTomato− cells (paired analysis, n=4 animals). B) Unsupervised hierarchical clustering (Ward's method) of hepPDs (n=5) bilPDs (n=5), and hepatocytes (n=3). C) Gene expression levels (RPKM) for progenitor associated genes and D) Hepatocyte-associated genes (mean ± s.d.). E) Cluster analysis shows hepPDs express biliary progenitor associated genes and a distinctive mesenchymal signature.