Table 1.
Demographics and baseline clinical characteristics
| Total CHR N =100 |
CHR+ N = 26 |
CHR− N = 74 |
|
|---|---|---|---|
| Demographics | Mean (SD) | Mean (SD) | Mean (SD) |
| Age (mean (SD)) | 20.1 (3.8) | 20.0 (3.9) | 20.1 (3.8) |
| N/% | N (%) | N (%) | |
| Male | 76 (76) | 21 (81) | 55 (74) |
| Ethnicity (self-reported)1 | |||
| Caucasian | 43 (43) | 8 (31) | 35 (47) |
| Latino | 32 (32) | 9 (35) | 23 (31) |
| African-American | 13 (13) | 4 (15) | 9 (12) |
| Asian-American | 9 (9) | 4 (15) | 5 (7) |
| More than one | 3 (3) | 1 (4) | 2 (3) |
| Full time employment/education | 63 (63) | 13 (50) | 50 (68) |
| Antipsychotic use at baseline | 14 (14) | 4 (15) | 10 (14) |
| Antidepressant use at baseline | 22 (22) | 4 (15) | 18 (24) |
| Cannabis use | 23 (23) | 6 (23) | 17 (23) |
| Symptoms | Mean (SD) | Mean (SD) | Mean (SD) |
| Positive symptoms (SIPS/SOPS) | |||
| Total | 13.0 (4.5) | 13.5 (4.9) | 12.8 (4.4) |
| Unusual thought content | 3.5 (1.3) | 3.7 (1.4) | 3.4 (1.2) |
| Suspiciousness | 3.0 (1.4) | 3.0 (1.5) | 3.0 (1.5) |
| Grandiosity | 1.7 (1.6) | 1.3 (1.7) | 1.9 (1.5) |
| Perceptual abnormalities | 2.6 (1.6) | 2.7 (1.9) | 2.6 (1.5) |
| Disorganized communication * | 2.2 (1.5) | 2.8 (1.5) | 2.0 (1.5) |
| Negative symptoms (SIPS/SOPS) | |||
| Total | 13.8 (6.6) | 15.4 (7.4) | 13.3 (6.3) |
| Social isolation and withdrawal | 3.2 (1.8) | 3.7 (1.8) | 3.0 (1.8) |
| Avolition | 2.7 (1.7) | 2.8 (1.6) | 2.7 (1.8) |
| Decreased expression of emotion | 1.5 (1.6) | 1.8 (1.8) | 1.4 (1.6) |
| Decreased experience of emotion | 1.6 (1.5) | 1.8 (1.6) | 1.5 (1.5) |
| Decreased ideational richness | 1.2 (1.4) | 1.4 (1.5) | 1.1 (1.4) |
| Deterioration in role function | 3.6 (1.8) | 3.9 (1.7) | 3.5 (1.9) |
Note: CHR+ are clinical high-risk patients who developed psychosis and CHR− are clinical high-risk patients who did not develop psychosis, within 2.5 years following baseline assessment.
*
indicates significant in stepwise logistic and Cox regression tests, p < 0.05, two-tailed.
1
Ethnic differences in risk for psychosis were tested by comparing ethnic minority to Caucasian respondents, due to limited statistical power when considering each ethnic group separately.