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Risk classification of GISTs
| Risk classification | Tumor size (cm) | Mitotic rate per 50 HPF | Tumor site |
|---|---|---|---|
| Very low risk | <2 | <=5 | Any |
| Low risk | 2.1-5.0 | <=5 | Any |
| 2.1-5.0 | >5 | Gastric | |
| Intermediate risk | <5 | 6-10 | Any |
| 5.1-10 | <=5 | Gastric | |
| High risk | Any | Any | Tumor rupture |
| >10 | Any | Any | |
| Any | >10 | Any | |
| >5 | >5 | Any | |
| 2.1-5.0 | >5 | Non gastric | |
| 5.1-10.0 | <=5 | Non gastric |
HPF = high power field.
