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. 2014 Nov 19;15(1):998. doi: 10.1186/1471-2164-15-998

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© Yin et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Highest scoring miRNA-mRNA interaction network, “Cellular Movement, Neurological Diseases, Organismal Injury and Abnormalities.” Figure was generated based on IPA software analysis of up-regulated miRNAs (maturation/secretory (M/S)) and their predicted gene target candidates that were down-regulated (M/S) with a top score of 110 and involvement of 62 molecules. The miRNA hubs, the genes that have multiple potential miRNA regulators, and the experimentally validated genes are colored red, blue and orange, respectively. The remaining genes in the network are colored green.