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. Author manuscript; available in PMC: 2015 Oct 20.
Published in final edited form as: Curr Biol. 2014 Sep 25;24(20):2399–2405. doi: 10.1016/j.cub.2014.08.040

Figure 2.

Figure 2

Recovery quiescence displays sleep-like properties and requires components of EGF signaling. A, Reversibility of locomotor quiescence after perturbation by harsh touch at 10, 20, and 30 minutes after a 30 min 35°C heat shock. B and C, Fraction of heat shocked wild-type young adults that do not show locomotor response within 5 seconds after a 3 second exposure to blue light (B) or during 5 second exposure to 1-octanol (C). D and E, Time course of feeding quiescence (D) and locomotor quiescence (E) following a 30 min 35°C heat shock in wild-type, lin-3(n1058) itr-1(sy290), let-23(sy10) unc-4(e120) and plc-3(tm1340) animals. let-23 and plc-3 mutants show impaired feeding quiescence at all time points, and lin-3 mutants at time points indicated by asterisks. The failure of lin-3 mutant animals to recover activity may reflect altered kinetics of ligand release caused by the n1058 intracellular domain mutation. Locomotion data was not collected for let-23 mutant animals due to a movement defect conferred by the unc-4(e120) mutation. Mean and SEM are shown. *p < 0.05, **p < 0.01, ***p < 0.001; Fisher’s exact test (A–D) and Student’s t test (E).