Table 8.

Visual acuity at baseline and at Week 104 by between eyes with and without outer retinal tubulation (ORT) at Week 104 (N=368)

Fluid and ORT status at Week 104	N	Visual Acuity
		Baseline: Mean (SE)	Week 104: Mean (SE)	Change at Week 104: Mean (SE)	≥20/40 at Week 104 n (%)	≤20/200 at Week 104 n (%)
ORT and IRF
No IRF	170	63.9 (1.0)	73.5 (1.4)	9.55 (1.33)	127 (74.7%)	1 (0.6%)
IRF with ORT	59	54.8 (1.6)	57.3 (2.33)	2.42 (2.25)	25 (42.4%)	13 (22.0%)
IRF without ORT	139	60.8 (1.1)	63.3 (1.52)	2.44 (1.47)	76 (54.7%)	14 (10.1%)
P value*		<0.0001	<0.0001	0.0005	<0.0001	<0.0001
ORT and SRF
No SRF	221	59.4 (0.8)	64.3 (1.25)	4.88 (1.19)	125 (56.6%)	23 (10.4%)
SRF with ORT	25	60.2 (2.5)	64.7 (3.72)	4.44 (3.53)	14 (56.0%)	2 (8.0%)
SRF without ORT	121	65.2 (1.2)	72.5 (1.69)	7.34 (1.60)	89 (73.6%)	3 (2.5%)
P value*		0.0003	0.0004	0.44	0.005	0.02
ORT and IRF/SRF
No IRF/SRF	91	61.4 (1.3)	71.0 (1.9)	9.64 (1.84)	60 (65.9%)	1 (1.1%)
IRF/SRF with ORT	64	54.8 (1.6)	58.5 (2.3)	3.69 (2.19)	29 (45.3%)	13 (20.3%)
IRF/SRF without ORT	213	63.2 (0.87)	67.9 (1.27)	4.66 (1.20)	139 (65.3%)	14 (6.6%)
P value*		<0.0001	0.0001	0.047	0.014	<0.0001
ORT
No	304	62.6 (0.73)	68.8 (1.06)	6.15 (1.01)	199 (65.5%)	15 (4.9%)
Yes	64	54.8 (1.58)	58.5 (2.32)	3.69 (2.20)	29 (45.3%)	13 (20.3%)
P-value*		<0.0001	<0.0001	0.31	0.004	<0.0001

^*From Fisher exact test for comparison of proportions, and two group t-test for comparison of means.

IRF = intraretinal fluid; SRF = subretinal fluid