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. Author manuscript; available in PMC: 2015 Nov 20.
Published in final edited form as: Chem Biol. 2014 Oct 9;21(11):1445–1451. doi: 10.1016/j.chembiol.2014.08.019

Figure 2. Specificity of the Tetravalent Allergens.

Figure 2

RBL cells were primed with (A) IgEDNP, (B) IgEdansyl, and (C) IgEcyclin A then exposed to increasing concentrations of the synthetic allergens HmTA [DNP4], HmTA [dansyl4], and HmBA [DNP2] to determine maximum degranulation response. HmTA [DNP4] and HmTA [dansyl4] only stimulated a response when the RBL cells were primed with IgEDNP and IgEdansyl respectively. HmBA [DNP2] did not stimulate a response under any condition. Data represents the means ± SD of triplicate experiments.