Table 4.
Frequency of all possible combinations of systemic inflammatory response syndrome (SIRS) criteria and the diagnostic characteristics for critical illness in admitted emergency department (ED) patients, n = 1152.a,b,c
| All patients
|
Measures of accuracy
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n = 1152 | ||||||||||
|
| ||||||||||
| Temperature criterion | Heart rate criterion | Respiratory rate criterion | WBC criterion | No. | (%) | Sn (%) | 95 % CI (%) | Sp (%) | 95% CI (%) | |
| - | - | - | - | 29 8 |
26 | 15 | 11, 20 | 71 | 68, 74 | |
| X | - | - | - | 89 | 8 | 5 | 3, 9 | 92 | 89, 93 | |
| - | X | - | - | 21 1 |
18 | 17 | 13, 22 | 81 | 79, 84 | |
| - | - | X | - | 32 | 3 | 2 | 1, 4 | 97 | 96, 98 | |
| - | - | - | X | 76 | 7 | 9 | 6, 13 | 94 | 92, 95 | |
|
| ||||||||||
SIRS
|
X | X | - | - | 54 | 5 | 5 | 3, 9 | 95 | 94, 97 |
| X | - | X | - | 17 | 1 | 0 | 0, 1 | 98 | 97, 99 | |
| X | - | - | X | 22 | 2 | 2 | 1, 5 | 98 | 97, 99 | |
| - | X | X | - | 97 | 8 | 14 | 10, 19 | 93 | 91, 95 | |
| - | X | - | X | 87 | 8 | 8 | 5, 12 | 93 | 91, 94 | |
| - | - | X | X | 14 | 1 | 1 | 0, 3 | 99 | 98, 99 | |
| X | X | X | - | 30 | 3 | 4 | 2, 7 | 98 | 97, 99 | |
| X | X | - | X | 33 | 3 | 4 | 2, 8 | 98 | 96, 99 | |
| X | - | X | X | 8 | 1 | 1 | 0, 3 | 99 | 99, 100 | |
| - | X | X | X | 49 | 4 | 7 | 5, 11 | 97 | 95, 98 | |
| X | X | X | X | 35 | 3 | 5 | 3, 9 | 98 | 96, 99 | |
Abbreviations: SIRS, systemic inflammatory response syndrome; ED, emergency department; WBC, white blood cell count; Sn, sensitivity; Sp, specificity; CI, confidence interval.
SIRS was defined as 2 or more of the following: temperature >38° C or <36° C; heart rate >90 per minute; respiratory rate >20 per minute; or white blood cell count (WBC) >12,000 or <4,000/μL.
53 patients were missing 1 of the 4 SIRS criteria variables. All instances of missing criteria variables were assumed to not have met that specific SIRS criterion.
Critical illness defined as ≥24 hours in the intensive care unit or in-hospital death.