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. Author manuscript; available in PMC: 2015 Oct 28.
Published in final edited form as: J Am Coll Cardiol. 2014 Oct 21;64(17):1765–1774. doi: 10.1016/j.jacc.2014.07.979

Central Illustration. Consort diagram showing cluster methodology applied to HF-ACTION study and the four distinct clusters that emerge.

Central Illustration

Interaction between exercise therapy and patient clusters extracted from the study. Symbols represent Hazard Ratios (HR) and 95 % Confidence Intervals (CI), with HR < 1.00 denoting benefit from exercise, and HR > 1.00 denoting harm.