. Author manuscript; available in PMC: 2015 Dec 1.

Published in final edited form as: Am Heart J. 2014 Jul 28;168(6):823–829.e6. doi: 10.1016/j.ahj.2014.07.016

Table 3.

Timetable of Assessments

	Screen- ing	Base- line	Week 2,4,6, 8,10,12	Month			Q 4M	Q 12M	EXIT
	Screen- ing	Base- line	Week 2,4,6, 8,10,12	4	8	12	Q 4M	Q 12M	EXIT
Physical examination¹	X					X		X	X
Medical history	X	X
Blood test
Hemoglobin	X
HbA1c	X
Alanine transaminase	X					X		X	X
Fasting glucose	X					X		X	X
Fasting lipid profile	X					X		X
Fasting insulin	X					X
HS C-reactive protein	X					X

NIH Stroke Scale		X
Medication inventory		X				X		X	X
Modified Mini-mental Exam		X				X		X	X
Lifestyle survey³		X				X		X	X

Safety and outcome screening ⁴			X	X	X	X	X	X	X
Study medication dose changes			4 and 8 weeks
Study medication resupply			12 weeks		X	X	X	X	X

Blood pressure, weight, height, edema grade, waist and hip measurements.

Tobacco use, alcohol use, exercise habits.

⁴

Self-reported weight, edema symptoms, shortness of breath, muscle aches, macroscopic hematuria; new diagnoses of stroke, MI, diabetes, CHF, cancer, fracture, macular edema; all hospitalizations.