Scheme 1.
One-pot synthesis of 2,4 diaminothiazole derivative (4). Reagents and conditions: (i) Cyanamide, KOtBu, ACN, t-BuOH, 30 °C, 2 h, 59%.
One-pot synthesis of 2,4 diaminothiazole derivative (4). Reagents and conditions: (i) Cyanamide, KOtBu, ACN, t-BuOH, 30 °C, 2 h, 59%.