Table 3.

Sources and calculated properties of virtual screening hits

Compound #	CDK5/ p25 Glide Score	CDK2 Glide Score	Sources	LogP (o/w)	LogBB	# Metab
5	−7.827	−3.673	Synthesized in-house	2.066	−0.823	2
6	−8.201	−4.069	Chem Bridge	4.071	−1.193	3
7	−9.221	−4.775	Ryan Sci.	3.685	−1.664	5
8	−7.582	−3.973	Ryan Sci.	1.233	−1.767	2
9	−8.007	−4.332	Chem Div	2.557	−2.107	6
10	−9.469	−5.539	Synthesized in-house	2.548	−1.020	4
11	−8.612	−5.240	Chem Bridge	4.134	−1.023	5
12	−8.908	−5.570	Ryan Sci.	1.522	−1.329	5
13	−7.864	−5.065	Chem Div	3.802	−1.115	3
14	−9.730	−8.117	Synthesized in-house	1.418	−1.027	2