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. Author manuscript; available in PMC: 2015 Nov 17.
Published in final edited form as: Curr Biol. 2014 Oct 30;24(22):2622–2631. doi: 10.1016/j.cub.2014.09.047

Figure 3. Cep290 is Essential for Drosophila Sperm Ciliogenesis.

Figure 3

(A-C) Cep290 is essential for spermatid axoneme formation. (A) Cross-section through a spermatid cyst in control, and (B) cep290mecH/- shows missing or defective axonemes (red arrows) and abnormal mitochondria (yellow arrows). Scale bars, 1 μm and 100 nm. Quantified in (C). N=10. (D-E) Centrioles of cep290mecH spermatocytes (C) and spermatids (D) are intact. Scale bar, 100 nm. (F-G) Cep290 is essential for centriole length. (F) Mature spermatocyte (S6) and spermatid (S17) centrioles are long in cep290mecH. Centriole length is normal before the onset of ciliogenesis (S2a). Stages described in [46]. Scale bars, 10 μm and 1 μm. (G) Quantification of Ana1-GFP length. N≥40. Also, see Figure S1.