Figure 2. Third trimester alcohol exposure blunted the LPS-induced increase in IL-1β mRNA expression in the frontal cortex of female pups but not males.
The fold change in mRNA expression represents the ratio of levels in LPS-injected pups over saline-injected littermates. Data is displayed as in Figure 1. The LPS-induced fold change in IL-1β mRNA expression was significantly attenuated in female rats of the PAE group compared to female rats in the air control group. (N.S. = not significant, * p ≤ 0.05 vs. a theoretical mean of 1, *** p ≤ 0.001 vs. Air control).