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. Author manuscript; available in PMC: 2015 Nov 15.
Published in final edited form as: Bioorg Med Chem. 2014 Oct 2;22(22):6360–6365. doi: 10.1016/j.bmc.2014.09.055

Figure 1.

Figure 1

Preparation of monovalent and bivalent ligands. Reagents and conditions: (a) 1:1 or 1:4 piperidine in DMF; (b) Standard solid phase synthesis using Fmoc-chemistry; (c) PEGO attachment (Ref. 3); (d) Ac2O/pyridine (50/50); (f) TFA/EDT/thioanisole/water (91/3/3/3).