Table IV.
Adjusted Odds Ratios for Associations of Positive ucAPI, Persistent Wheezing, Atopic Persistent Wheezing and Non-atopic Persistent Wheezing at Age 3 With Asthma Outcome at Age 7 in Separate Logistic Regression Models.
| Exposure/Covariate | aOR (95% CI) for Asthma at 7 years [p-value^] |
|||
|---|---|---|---|---|
| ucAPI Model |
Persistent Wheezing Model |
Atopic Persistent Wheezing Model |
Non-atopic Persistent Wheezing Model |
|
| Positive ucAPI at 3 years | 13.27 (7.0–25.15) <0.01 | - | - | - |
| Persistent Wheezing at 3 years | - | 9.81 (4.93–19.52) <0.01 | - | - |
| Atopic Persistent Wheezing at 3 years | - | - | 10.35 (4.12–26.01) <0.01 | - |
| Non-atopic Persistent Wheezing at 3 years | - | - | - | 5.36 (2.04–14.06) <0.01 |
| Household income < $20K | 3.64 (1.94–6.82) <0.01 | 3.61 (1.91–6.81) <0.01 | 3.62 (1.95–6.75) <0.01 | 3.61 (1.96–6.68) <0.01 |
| Parental Asthma | € | 1.87 (1.08–3.23) 0.026 | 2.03 (1.19–3.47) <0.01 | 2.12 (1.26–3.56) <0.01 |
| Sensitization to Egg at 1year | 2.82 (1.43–5.57) <0.01 | 2.92 (1.45–5.90) <0.01 | 2.61 (1.32–5.16) 0.006 | 2.84 (1.46–5.54) <0.01 |
| Eczema | € | 2.06 (1.14–3.74) 0.017 | 2.02 (1.12–3.64) 0.02 | 2.35 (1.34–4.14) <0.01 |
| Daycare attendance | 1.77 (1.02–3.08) 0.042 | 1.59 (0.91–2.78) 0.103 | 1.81 (1.05–3.11) 0.03 | 1.73 (1.01–2.95) 0.04 |
| Dog ownership | 0.55 (0.31–0.99) 0.045 | * | * | * |
| ECAT exposure ≥ 75th percentile from birth-3years | * | * | * | * |
ucAPI: University of Cincinnati API
aOR = adjusted odds ratio
Significant at p ≤ 0.10
- Not included in the model
Not included in the model because it was one of the defining criteria for a positive ucAPI
Not significant at p ≤ 0.10
The initial multivariate models included all covariates (except when denoted by - or €), including gender, race, exposure to environmental tobacco smoke, breast feeding, sensitization to aeroallergens, egg and milk at 1 and 3 years of age, cat ownership, and ECAT exposure ≥ 75th percentile between birth to 3years of age but were not significant an alpha of 10%.