Table 3.

Moderate to severe side effects of aggressive treatment in the juvenile dermatomyositis patients (n = 49)^*

Abdominal distress/pain	1 (2)
Acute psychosis	1 (2)
Fractures†	5 (10)
Hypertension	3 (6)
Infections‡	2 (4)
Mood swings	1 (2)

^*Moderate to severe side effects were evaluated as grade 3 or higher according to the Common Toxicity Criteria of the National Cancer Institute (25). Values are the number (%) of patients.

^†One humeral, 1 radial, 2 tibial, and 1 vertebral compression fracture.

^‡Rotavirus and diarrhea, requiring fluid resuscitation and admission to the intensive care unit, and axillary furuncle, requiring intravenous antibiotics.