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. Author manuscript; available in PMC: 2015 Jul 18.
Published in final edited form as: Circ Res. 2014 Jun 10;115(3):376–387. doi: 10.1161/CIRCRESAHA.115.304441

Figure 4. Mitochondrial morphological and functional aberrations with loss of Pim.

Figure 4

A) Electron microscopy scans of NTG (n=3) and PTKO (n=3) hearts at one month and quantification of mitochondrial area and mitochondrial area per section. B) Protein analysis of VDAC in NTG (n=4) and PTKO (n=4) mouse hearts. C) Citrate synthase activity in cardiac lysates of NTG (n=6) and PTKO (n=6) mice. D) Total ATP levels in NTG (n=13) and PTKO (n=10) heart lysates. E) Immunoblot for pAMPK and total AMPK and analysis of pAMPK : AMPK ratio in cardiac samples of NTG (n=6) and PTKO (n=6) mice. * and ** is significant compared to NTG mice. *P < 0.05 and **P < 0.01.