A) mRNA levels of PGC-1α, PGC-1β, Errα, NRF1, and TFAM in 1 month NTG (n=6) and PTKO (n=6) hearts. B-D) Protein analysis of PGC-1α, PGC-1β, and c-Myc respectively in cardiac samples; NTG (n=6) and PTKO (n=7) hearts. E-F) Mitochondrial DNA analysis of Cox1 and Cytochrome B normalized to β-globin; NTG (n=4) and PTKO (n=4). * and ** is significant compared to NTG mice. *P < 0.05 and **P < 0.01.