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. Author manuscript; available in PMC: 2015 Jul 18.
Published in final edited form as: Circ Res. 2014 Jun 10;115(3):376–387. doi: 10.1161/CIRCRESAHA.115.304441

Figure 6. Alterations in metabolic gene expression profile ensue with loss of Pim kinases.

Figure 6

mRNA levels of A) Fatty acid oxidation genes (Enzymes: Acate3, acyl coenzyme A thioesterase 3, mitochondrial; Acadv1, aceyl coenzyme A long chain; Acadm, FAO-acetyl CoenzymeA dehydrogenase. Transporters: Cpt1b, carnatine palmitoyl transferase; Cpt2, carnatine palmitoyl transferase 2. B) Glycolysis genes (Hk2, hexokinase 2; Pdk4, pyruvate dehydrogenase kinase 4; Pfk, phosphofructokinase; PDHA1, pyruvate dehydrogenase E1 alpha 1; PFKFB2, (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2). C) Oxidative Phosphorylation (OXPHOS) (Cytc, cytochrome c; Ndufa, NADH dehydrogenase 1 alpha subcomplex subunit 1; Ndufv, NADH dehydrogenase ubiquinone flavoprotein 1); Idh2, isocitrate dehydrogenase 2. n=6 NTG and n=6 PTKO. *, **, *** is significant compared to NTG mice. *P < 0.05; **P < 0.01; ***P < 0.001.