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. Author manuscript; available in PMC: 2014 Dec 4.
Published in final edited form as: Am J Physiol Gastrointest Liver Physiol. 2008 Apr 24;294(6):G1376–G1383. doi: 10.1152/ajpgi.00078.2008

Fig. 4.

Fig. 4

Forskolin reduces synaptic rundown and accelerates rundown recovery after a stimulus train. A. Forskolin (1 μM) increased fEPSP amplitude but it did not change the time constant of rundown. Data are mean ± s.e.m. (n = 8). B. Forskolin decreased the time constant for recovery of fEPSP amplitude after synaptic rundown. Recovery is expressed as the ratio of fEPSPtest to fEPSPfirst where fEPSPfirst is the first fEPSP in the stimulus train and fEPSPtest is the amplitude of the fEPSP evoked at various times after the end of the stimulus train. Solid lines are monoexponential fits to the data points in each group. Data points are mean ± s.e.m. (n = 8).