Table 1.

Analysis of detector patch data obtained from outside-out patches obtained from neurons in 5 different culture preparations. A patch was positioned within 2 μm of a varicosity and each patch was tested against 20 stimuli applied to the axon containing the test varicosity before and after renzapride (0.1 μM) application. Failures were stimuli that did not evoke single channel activity in the detector patch; successes evoked single channel activity. Renzapride increased the proportion of successful stimuli (^#P < 0.001 vs. control, Fischer’s Exact test). Charge transfer was measured as the area under the single channel current time curve (200 ms). Renzapride increased total charge transfer because it increased the number of successful stimuli (* P < 0.05 vs control). Charge transfer per success was not changed by renzapride.

	Failures	Successes	Total charge transfer (pA·ms)	Charge transfer per success (pA·ms)
Control	73	27	64 ± 9	283 ± 47
Renzapride	48	52#	216 ± 47*	372 ± 52