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Changes in inflammatory gene expression in response to IL-1β in siFOXO transfected chondrocytes.
Human chondrocytes transfected with siRNA were stimulated with or without IL-1β (0.01 ng/ml) for 6 h. Inflammatory gene expression was analyzed by real-time PCR using primers as indicated. Graph shows the results of a total of 5 donors (N=5). Values are the mean and SD. * = P < 0.05 and ** = P < 0.01 versus siCtrl.
