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Changes in ADAMTS-4 and Chemerin production in response to IL-1β in siFOXO transfected chondrocytes.
Human chondrocytes transfected with siRNA were stimulated with IL-1β (0.1 ng/ml) for 24 h. ADAMTS-4 protein was analyzed by western blot and Chemerin protein in the supernatant was measured by ELISA. Graph shows the results of a total of 4 donors (N=4). Values are the mean and SD. * = P < 0.05 and ** = P < 0.01 versus siCtrl.
