Table 2. Mean ankle-brachial index (ABI), common carotid artery intima-media thickness (CCA-IMT), and internal carotid artery IMT (ICA-IMT) by sex-specific quartile of trabecular lumbar bone mineral density (vBMD), MESA, Abdominal Aortic Calcium Study, 2000-2005.
WOMEN | MEN | |||||
---|---|---|---|---|---|---|
Model 1 * | Model 2 † | Model 3 ‡ | Model 1 * | Model 2 † | Model 3 ‡ | |
n=904 | n=868 | n=807 | n=929 | n=898 | n=884 | |
Mean±SD | Mean±SD | Mean±SD | Mean±SD | Mean±SD | Mean±SD | |
Mean ABI | ||||||
vBMD Q1 | 1.09±0.007 | 1.08±0.008 | 1.08±0.009 | 1.12±0.008 | 1.11±0.008 | 1.11±0.008 |
vBMD Q2 | 1.10±0.007 | 1.09±0.007 | 1.09±0.008 | 1.14±0.007 | 1.13±0.008 | 1.13±0.008 |
vBMD Q3 | 1.08±0.007 | 1.08±0.007 | 1.08±0.008 | 1.15±0.007 | 1.15±0.008 | 1.15±0.008 |
vBMD Q4 | 1.10±0.007 | 1.09±0.008 | 1.09±0.009 | 1.14±0.007 | 1.13±0.008 | 1.14±0.008 |
p for ANCOVA | 0.119 | 0.202 | 0.215 | 0.017 | 0.007 | 0.004 |
p for trend | 0.828 | 0.928 | 0.976 | 0.041 | 0.017 | 0.009 |
Mean ICA-IMT
§
(mm) | ||||||
vBMD Q1 | 0.90±0.03 | 0.97±0.04 | 0.98±0.04 | 1.01±0.03 | 1.04±0.03 | 1.05±0.03 |
vBMD Q2 | 0.86±0.03 | 0.89±0.03 | 0.91±0.03 | 0.95±0.03 | 0.96±0.03 | 0.97±0.03 |
vBMD Q3 | 0.87±0.03 | 0.89±0.03 | 0.91±0.03 | 0.96±0.03 | 0.99±0.03 | 0.98±0.03 |
vBMD Q4 | 0.86±0.03 | 0.89±0.03 | 0.89±0.03 | 0.91±0.03 | 0.93±0.03 | 0.93±0.03 |
p for ANCOVA | 0.703 | 0.167 | 0.163 | 0.106 | 0.061 | 0.053 |
p for trend | 0.462 | 0.106 | 0.071 | 0.033 | 0.023 | 0.015 |
Mean values are geometric means for ICA-IMT
Adjusted for age and race/ethnicity.
Adjusted for age, race/ethnicity, body mass index, total cholesterol, HDL, use of cholesterol medication, hypertension, diabetes, cigarette smoking, alcohol consumption, physical activity, homocysteine, C-reactive protein, interleukin-6 and hormone therapy (women only)
Adjusted for age, race/ethnicity, body mass index, total cholesterol, HDL, use of cholesterol medication, hypertension, diabetes, cigarette smoking, alcohol consumption, physical activity, homocysteine, C-reactive protein, interleukin-6 and unordered quartiles of total testosterone, sex hormone binding globulin and estradiol. In women, these quartiles are specific for women taking and not taking supplemental estrogens.