TABLE II.
Eligible
|
Ineligible
|
P values*
|
|||||
---|---|---|---|---|---|---|---|
(1) | (2) IgE <30 IU/mL | (3) IgE/weight | (4) IgE >1300 IU/mL | (1) vs (2), (3) & (4) | (1) vs (2) | (1) vs (3) & (4) | |
No. of participants | 596 | 83 | 107 | 103 | |||
| |||||||
Age (y), mean ± SD | 10.7 ± 3.6 | 10.1 ± 3.9 | 11.0 ± 3.4 | 14.0 ± 3.0 | <.001 | .10 | <.001 |
| |||||||
Symptoms, mean ± SD | |||||||
| |||||||
Nights awoken (past 4 wk) | 11.5 ± 6.7 | 11.2 ± 6.6 | 11.3 ± 7.3 | 11.4 ± 6.9 | .80 | .58 | .99 |
| |||||||
Days of wheeze (past 2 wk) | 4.3 ± 2.2 | 4.2 ± 2.3 | 4.7 ± 2.2 | 4.5 ± 2.2 | .39 | .53 | .15 |
| |||||||
No. of albuterol uses (past 2 wk) | 14 ± 11 | 14 ± 12 | 14 ± 12 | 16 ± 12 | .88 | .68 | .66 |
| |||||||
Health care utilization in past year (%) | |||||||
| |||||||
Any hospitalizations | 28 | 12 | 25 | 25 | .03 | <.01 | .32 |
| |||||||
Any unscheduled visits | 81 | 91 | 84 | 84 | .13 | .02 | .60 |
| |||||||
On daily controller medications | 89 | 78 | 85 | 85 | .06 | <.01 | .42 |
| |||||||
Allergen skin tests | |||||||
| |||||||
No. positive (of 14), mean ± SD | 4.4 ± 2.7 | 2.6 ± 2.1 | 5.6 ± 2.8 | 5.6 ± 2.8 | .20 | <.001 | <.001 |
| |||||||
Dog (%) | 30 | 19 | 29 | 35 | .49 | .03 | .67 |
| |||||||
Cat (%) | 52 | 21 | 65 | 66 | .75 | <.001 | <.001 |
| |||||||
Mouse (%) | 31 | 15 | 49 | 41 | .15 | <.01 | <.001 |
| |||||||
Der f (%) | 38 | 27 | 58 | 57 | <.01 | .07 | <.001 |
| |||||||
Der p (%) | 45 | 28 | 63 | 56 | .13 | <.01 | <.001 |
| |||||||
German roach (%) | 50 | 17 | 61 | 62 | .70 | <.001 | <.01 |
| |||||||
Roach mix (%) | 52 | 30 | 65 | 68 | .25 | <.001 | <.001 |
The 3 P values test for differences between: eligible and all ineligible participants, eligible participants and participants who were excluded because of low IgE, and eligible participants and participants who were excluded because of either high IgE or a combination of weight and IgE.