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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Arch Toxicol. 2014 Jun 3;89(6):967–977. doi: 10.1007/s00204-014-1285-8

Fig 3.

Fig 3

Acute histological changes (A) in the liver of mice treated with reconstituted mixture (RM). Panel a: control, mouse treated with corn oil/DMSO (50:50). Panel b: mouse treated with the high dose of the reconstituted mixture (RM). Seven days after treatment, focal hemorrhage and tissue necrosis were observed. (B) PAH-induced hepatic tumor formation. Panel c: gross tumor formation observed in the high dose NF+BaP group during dissection. Panel d: liver tissue from control group treated with corn oil/DMSO (50:50). Panel e: liver hepatoma observed in the high dose NF+BaP group. All samples were obtained at 280 d after PAH treatment. NF, neutral fraction.