. 2014 Dec 3;9(12):e114123. doi: 10.1371/journal.pone.0114123

Table 1. Purity analysis of untreated control vs. post-isolation AuNP-spiked RNA samples.

Sample	Without RNAprotect solution						With RNAprotect solution						Comments
	Average A₂₆₀/A₂₈₀	Std Dev A₂₆₀/A₂₈₀	Average A₂₆₀/A₂₃₀	Std Dev A₂₆₀/A₂₃₀	Average yield compared to control	p-Value	Average A₂₆₀/A₂₈₀	Std Dev A₂₆₀/A₂₈₀	Average A₂₆₀/A₂₃₀	Std Dev A₂₆₀/A₂₃₀	Average yield compared to control	p-Value
Control	2.053	0.037	1.483	0.210	100%	N/A	2.036	0.045	1.916	0.055	100%	N/A	Good quantity and purity.
Control + 25% AuNP	2.053	0.045	1.366	0.118	83.31%	0.029*	2.05	0.045	1.743	0.180	73.70%	0.016*	Reduced yield; no protein contamination; no contaminants from isolation procedure when Protect solution used.
Control + 50% AuNP	2.033	0.075	1.333	0.058	57.62%	0.001***	2.05	0.043	1.870	0.105	58.92%	0.001***	Reduced yield; no protein contamination; no contaminants from isolation procedure when Protect solution used.
Control + 75% AuNP	2.006	0.050	1.356	0.208	45.72%	0.006**	2.02	0.062	1.763	0.125	36.91%	1.743E-05 ***	Reduced yield; no protein contamination; no contaminants from isolation procedure when Protect solution used.

Note: *** p≤0.005; ** 0.005≤p≤0.01; * 0.01≤p≤0.05. (Std Dev) Standard Deviation.