Fig. 7.

Protein levels for dihydropyridine receptor α1 subunit (DHPR-α1) in superficial GAS muscle of WT and ALS Tg mice. Protein levels for DHPR-α1 were determined by Western blot analysis and quantified by chemiluminescence. A: raw data shown for superficial GAS for 3 representative samples at 120–140 days. Membrane staining for total protein is shown to confirm equal loading. B: average luminescence values obtained by densitometric analysis and expressed as arbitrary units are shown for superficial GAS muscle. Data shown represent means ± SE for WT and ALS Tg mice at 120–140 days (n = 5); *P < 0.05 vs. WT.