Table 2.
Percentage of fibers failing to maintain peak Ca2+ transients in WT and G93A*SOD1 ALS Tg mice
| Stimulation Frequency, Hz | WT | ALS Tg |
|---|---|---|
| 10 | 0/18 (0%) | 1/21 (5%) |
| 30 | 1/18 (6%) | 3/21 (14%) |
| 50 | 2/18 (12%) | 5/21 (24%) |
| 70 | 3/18 (17%) | 7/21 (33%) |
| 100 | 4/18 (23%) | 9/21 (43%) |
A subset of muscle fibers from 120–140-day-old mice was assessed for the ability to sustain peak Ca2+ transients over the final 100 ms of the 350-ms tetanus. The number of fibers that failed to maintain the peak Ca2+ transient at each stimulation frequency is shown and presented as a % failing fibers.