Table 1.

Criteria used to calculate mitochondrial damage score

Damage Score	Morphological Appearance
0	Well-defined and organized membranes and cristae
1	Minor distortions and/or swellings, but general organization retained
2	Major distortions and/or swellings and discontinuous membranes and cristae
3	Membranes and cristae dissociated into particulates to produce diffuse mitochondrial ghosts
4	Only a few mitochondrial remnants in cells