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Conditional depletion of SMC EC-SOD did not impact lung phosphodiesterase 5 (PDE5) expression or activity. A: densitometry for PDE5 relative to β-actin in total lung homogenates from CO and KO mice exposed to normoxia and 35 days of hypoxia; n = 5–6. B: representative Western blot analysis for PDE5. C: PDE5 activity in lung homogenates from CO and KO mice exposed to normoxia or 35 days of hypoxia; n = 5–6.
