Table 1.

Characteristics of mice in the diabetes study

	Normal	Diabetes	Diabetes + l-Arginine	Diabetes + l-Citrulline
Number of mice/group	8	8	7	6
Body weight, g	29 ± 1.05	18 ± 0.61‡	18 ± 0.42‡	15 ± 0.33‡
Blood glucose, mg/dl	149 ± 5.37	499 ± 0.98*	495 ± 2.38*	500 ± 0.5*
Water consumed, ml/day	2.29 ± 0.37	6.00 ± 0.91*	7.26 ± 0.48*	5.18 ± 1.19*
Average amino acid consumed in drinking water, g·kg−1·day−1	0	0	6.05	5.73
Average nitrogen consumed in drinking water, mmol·kg−1·day−1	0	0	138.9	98.1
Systolic blood pressure, mmHg	122 ± 2.44	112 ± 4.03	111 ± 4.09	109 ± 8.25
Percent fluid	7.5 ± 0.13	6.6 ± 0.11*	5.5 ± 0.17*	5.8 ± 0.09*
Kidney weight/body weight, mg/g	0.92 ± 0.05	1.33 ± 0.02*	1.54 ± 0.03*	1.53 ± 0.05*
Plasma creatinine, mg/dl	0.26 ± 0.08	0.62 ± 0.11*	0.48 ± 0.04*	0.94 ± 0.16*

Data are means ± SE. Values were measured 9 wk after streptozotocin treatment.

^*P < 0.05 compared with the normal group;

^‡P < 0.0001 compared with the normal group.