Table 4.
Kiss-1 mRNA expression (grains/cell) in the ARC and the AVPV from intact, Ovx, and Ovx + E2-treated WT and kiss-p110α/β-KO female mice
| WT |
Kiss-p110α/β-KO |
|||||
|---|---|---|---|---|---|---|
| Females | Intact (n = 6) | Ovx + V (n = 6) | Ovx + E2 (n = 6) | Intact (n = 6) | Ovx + V (n = 6) | Ovx + E2 (n = 6) |
| Kiss-1 mRNA, grains/cell | ||||||
| ARC | 65.0 ± 2.1 | 96.2 ± 3.1** | 63.3 ± 2.1 | 61.8 ± 3.3 | 85.1 ± 8.8** | 58.2 ± 5.1 |
| AVPV | 88.4 ± 3.0 | 62.1 ± 2.9** | 75.5 ± 4.1 | 74.1 ± 1.7 | 51.4 ± 11.1** | 75.9 ± 5.6 |
Data are expressed as the means ± SE for each treatment and genotype.
**
P < 0.001, 2-way ANOVA: Ovx + V treatment compared with intact and Ovx + steroid hormone-treated group.