Figure 2.

Baseline LH secretion and responses to kisspeptin and GnRH in two representative male (♂) subjects. The phenotype, Kallmann syndrome (KS) or normosmic IHH (nIHH), and genotype are noted for each subject. Results for subject 1 before and after priming with exogenous GnRH are shown in panels A and B, respectively. Similarly, results for subject 6 before and after priming are shown in panels C and D, respectively. Arrows indicate times of boluses. T, testosterone levels during the study. FSH values measured from first 2-h pool.