Table 1.
Comparison Between Patients With Low T (≤12.1 nmol/L) and Normal T (≥12.1 nmol/L)
| Group | Low Total T (<12.1 nmol/L) | Normal Total T (≥12.1 nmol/L) | P Value |
|---|---|---|---|
| Number of patients, n | 36 | 79 | |
| Age, y | 59 ± 5.8 | 58 ± 7.01 | .78 |
| Diabetes duration, y | 7.9 ± 3.06 | 6.0 ± 3.19 | .06 |
| Weight, kg | 90 ± 9.8 | 88 ± 13.8 | .44 |
| BMI, kg/m2 | 29.8 ± 2.9 | 29.1 ± 3.9 | .27 |
| Triglycerides, mg/dL | 124 ± 27.9 | 130 ± 74.0 | .63 |
| LDL cholesterol, mg/dL | 127 ± 23.1 | 118 ± 24.5 | .17 |
| HDL cholesterol, mg/dL | 37 ± 6.8 | 41 ± 8.3 | .002 |
| HbA1c, % | 7.05 ± 0.58 | 6.9 ± 1.04 | .10 |
| Glucose, mg/dL | 133 ± 14.5 | 132 ± 28.3 | .92 |
| SHBG, nmol/L | 34.79 ± 10.4 | 42.76 ± 22.4 | <.001 |
| Total T, nmol/L (ng/L) | 10.03 ± 1.86 (2.9 ± 0.54) | 17.64 ± 4.53 (5.1 ± 1.31) | |
| Free T, pmol/L (pg/mL) | 202.3 ± 82 (58.3 ± 23.8) | 308 ± 176 (89.0 ± 51.0) | <.005 |
| Carotid IMT, cm | 0.107 ± 0.013 | 0.083 ± 0.019 | <.0001 |
| Endothelial dysfunction, n (% of patients) | 29/36 (80.5%) | 33/78. (42.3%) | <.003 |
| Plaque, n (% of patients) | 24/ 35 (68.5) | 35/78 (44,8%) | <.02 |
| C-reactive protein, mg/L | 2.74 ± 1.37 | 0.89 ± 0.93 | <.0001 |
Data are expressed as mean ± SE.