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. 2014 Sep 2;99(12):4555–4564. doi: 10.1210/jc.2014-2268

Figure 2.

Figure 2.

A. Forest plot of comparison of serum total calcium between juvenile PHPT and adult PHPT. Serum calcium in pediatric PHPT is significantly increased relative to Adult PHPT, P < .05 (paired t test with Welch's correction for unequal variances), pediatric mean, 3.2 mmol/L (95% CI, 2.8–3.4) vs 2.9 mmol/L (95% CI, 2.8–3.0). Summary or individual statistics for calcium were reported for all of the subjects in this study (n = 2673). Studies separating out multiple decades [Lo et al (24) and Mazzaglia et al (25)] are graphically represented by a square for each group. Square size is proportional to n and SD. B. Forest plot of comparison of serum PTH between juvenile PHPT and adult PHPT. Differences between groups are not statistically significant, P = .17 (paired t test with Welch's correction for unequal variances); pediatric mean, 35.1 pmol/L (95% CI, 12.2–58.0) vs 18.5 pmol/L (95% CI, 12.7–24). Summary or individual statistics for PTH were reported for 2388 subjects. Studies separating out multiple decades [Lo et al (24) and Mazzaglia et al (25)] are graphically represented by a square for each group. Square size is proportional to n and SD.