Table 2.

Lab Abnormalities Associated with Vandetanib and Cabozantinib in Order of Frequency

Vandetanib	Cabozantinib
Calcium decreased, 57%	AST increased, 86%
ALT increased, 51%	ALT increased, 86%
Glucose decreased, 24%	Alkaline phosphatase increased, 52%
Creatinine increased, 16%	Calcium decreased, 52%
Bilirubin increased, 13%	Phosphorus decreased, 28%
Magnesium decreased, 7%	Bilirubin increased, 25%
Potassium decreased, 6%	Magnesium decreased, 19%
Potassium increased, 6%	Potassium decreased, 18%
Neutropenia, 10%	Sodium decreased, 10%
Thrombocytopenia, 9%	Neutropenia, 35%
	Thrombocytopenia, 35%
	TSH increased, 57%

Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase.