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. Author manuscript; available in PMC: 2015 Dec 15.
Published in final edited form as: Bioorg Med Chem Lett. 2014 Nov 7;24(24):5568–5571. doi: 10.1016/j.bmcl.2014.11.010

Scheme 1.

Scheme 1

Synthesis of ketophosphonate (β-ketoP) and hydroxyphosphonate (β-hydroxyP) analogs of biotin-5′-AMP