. Author manuscript; available in PMC: 2015 Dec 15.

Published in final edited form as: Toxicol Appl Pharmacol. 2014 Oct 31;281(3):254–265. doi: 10.1016/j.taap.2014.10.009

Table 4.

Summary of Oximes Challenged with GA

Oxime Dose	Oxime	Oxime Dose (mg/kg)	24-hr Lethality	24-hr Mean QOL Score	24-hr Mean RA_AChE (%)	24-hr Mean RA_BChE (%)
Equimolar	MMB4 DMS	65.3	1/8^*	2.0^*	71^*	73
	HLö7 DMS	75.9	1/8^*	2.5^*	41	50
	Obidoxime	52.3	2/8^*	3.5	33	26
	HI-6 DMS	69.6	3/8^*	5.6	52	59
	2 PAM Cl	25.7	6/8	9.6	22	35
	RS194B	31	7/8	10.6	32	37
	MINA	12.7	7/8	11.3	28	53
	TMB4	15.8	8/8	12.0	-	-
	none	0.0	55/64 = 86%	10.8^†	35	49

Therapeutic	MMB4 DMS	104	0/8^*	0.0^*	75^*	110^*
	HI-6 DMS	110	0/8^*	1.3^*	53^*	58^*
	MINA	33.2	5/8	8.9	25	34
	RS194B	126	6/8	9.8	33	47
	none	0.0	28/32 = 88%	11^‡	24	33

Statistically significant at the 0.05 level compared to the control group

^†

pooled across 64 animals challenged as equimolar controls with GA.

^‡

pooled across 32 animals challenged as TI controls with GA.