A. Body weight curve for each experimental cohort (see Fig 1, Fig S1 and experimental procedures for cohort description). The number of mice (n) analyzed per group was (i-ii) n=16, (iii) n=12, and (iv) n=32 then 16.
B. Body composition of mice in each feeding group at the end of the study, and corresponding
C. total fat mass as a percent of total body weight. The percentage reduction of fat mass compared to ad libitum fed controls is indicated. (i-ii) n=4 and (iii-iv) n=8.
Data are presented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001 versus all other groups or versus the ad libitum fed control group as indicated.