Table 5. Sensitivity analysis of association between MTHFR C677T polymorphism and CHD.

		Test of heterogeneity			Test of association
Subgroup	Genetic model	Q	P	I2 (%)	OR	95% CI	Z	P
Children Overall	TT vs. CT	32.42	0.020	44.5	1.303	1.064–1.596	2.56	0.010
	Recessive model	61.61	0.000	70.8	1.335	1.028–1.735	2.16	0.030
Maternal Overall	T vs. C	32.48	0.006	53.8	1.215	1.042–1.425	2.48	0.013
	TT vs. CC	29.99	0.012	50.0	1.570	1.125–2.192	2.65	0.008
	TT vs. CT	26.09	0.037	42.5	1.462	1.104–1.937	2.65	0.008
	Dominant model	22.10	0.105	32.1	1.198	1.035–1.386	2.43	0.015
	Recessive model	29.49	0.014	49.1	1.527	1.149–2.030	2.92	0.004
Asian Maternal	T vs. C	3.96	0.412	0.0	1.595	1.348–1.886	5.45	5.04e-8
	TT vs. CC	3.49	0.479	0.0	2.548	1.788–3.631	5.18	2.22e-7
	TT vs. CT	1.51	0.825	0.0	1.884	1.415–2.509	4.34	1.42e-5
	Dominant model	4.93	0.295	18.9	1.605	1.215–2.121	3.33	0.001
	Recessive model	2.05	0.727	0.0	2.073	1.583–2.716	5.29	1.22e-7