Table 2.

Ordinal logistic regression of cumulative cannabis use at age 16 and PEs at age 18

Model	n = 1756 (excluding PEs at 12)			n = 1573 (excluding PEs at 12 and 16)
	OR	95% CI	p	OR	95% CI	p
1	1.48	1.18, 1.86	0.001	1.35	0.98, 1.86	0.070
2	1.53	1.21, 1.92	<0.001	1.40	1.01, 1.95	0.043
3	1.57	1.23, 2.00	<0.001	1.50	1.07, 2.10	0.019
4a	1.27	0.91, 1.76	0.160	1.08	0.69, 1.69	0.744
4b	1.57	1.19, 2.08	0.002	1.62	1.10, 2.39	0.015
4c	1.25	0.91, 1.73	0.165	1.30	0.84, 2.01	0.247
5	1.12	0.76, 1.65	0.553	1.09	0.65, 1.82	0.751

Model 1: PE at 18 by categorical cumulative cannabis use at 18.

Model 2: as model 1 with additional adjustment for pre birth confounders (family history of depression, family history of schizophrenia, gender, urban dwelling, maternal education).

Model 3: as model 2 with additional adjustment for childhood confounders (borderline personality, IQ at age 8, depression at age 12, conduct disorder trajectory group membership, peer problems, bullied).

Model 4a: as model 3 with additional adjustment for cigarette use.

Model 4b: as model 3 with additional adjustment for alcohol use.

Model 4c: as model 3 with additional adjustment for illicit drug use (other than cannabis).

Model 5: as model 3 with additional adjustment for cigarette, alcohol and other illicit drug use.