Table 2.
Model | n = 1756 (excluding PEs at 12) | n = 1573 (excluding PEs at 12 and 16) | ||||
---|---|---|---|---|---|---|
OR | 95% CI | p | OR | 95% CI | p | |
1 | 1.48 | 1.18, 1.86 | 0.001 | 1.35 | 0.98, 1.86 | 0.070 |
2 | 1.53 | 1.21, 1.92 | <0.001 | 1.40 | 1.01, 1.95 | 0.043 |
3 | 1.57 | 1.23, 2.00 | <0.001 | 1.50 | 1.07, 2.10 | 0.019 |
4a | 1.27 | 0.91, 1.76 | 0.160 | 1.08 | 0.69, 1.69 | 0.744 |
4b | 1.57 | 1.19, 2.08 | 0.002 | 1.62 | 1.10, 2.39 | 0.015 |
4c | 1.25 | 0.91, 1.73 | 0.165 | 1.30 | 0.84, 2.01 | 0.247 |
5 | 1.12 | 0.76, 1.65 | 0.553 | 1.09 | 0.65, 1.82 | 0.751 |
Model 1: PE at 18 by categorical cumulative cannabis use at 18.
Model 2: as model 1 with additional adjustment for pre birth confounders (family history of depression, family history of schizophrenia, gender, urban dwelling, maternal education).
Model 3: as model 2 with additional adjustment for childhood confounders (borderline personality, IQ at age 8, depression at age 12, conduct disorder trajectory group membership, peer problems, bullied).
Model 4a: as model 3 with additional adjustment for cigarette use.
Model 4b: as model 3 with additional adjustment for alcohol use.
Model 4c: as model 3 with additional adjustment for illicit drug use (other than cannabis).
Model 5: as model 3 with additional adjustment for cigarette, alcohol and other illicit drug use.