Table 4.
Model | n = 1756 (excluding PEs at 12) | n = 1573 (excluding PEs at 12 and 16) | ||||
---|---|---|---|---|---|---|
Odds Ratio | 95% CI | p value | Odds Ratio | 95% CI | p value | |
1 | 1.61 | 1.31, 1.98 | <0.001 | 1.62 | 1.23, 2.13 | 0.001 |
2 | 1.59 | 1.29, 1.96 | <0.001 | 1.60 | 1.21, 2.13 | 0.001 |
3 | 1.53 | 1.23, 1.91 | <0.001 | 1.63 | 1.22, 2.18 | 0.001 |
4a | 1.42 | 1.05, 1.92 | 0.022 | 1.67 | 1.14, 2.45 | 0.008 |
4b | 1.54 | 1.20, 1.98 | 0.001 | 1.85 | 1.32, 2.60 | <0.001 |
4c | 1.29 | 1.00, 1.68 | 0.051 | 1.52 | 1.09, 2.13 | 0.015 |
5 | 1.36 | 0.99, 1.86 | 0.055 | 1.77 | 1.18, 2.66 | 0.006 |
Model 1: PE at 18 by categorical frequency of cigarette use at 18.
Model 2: as model 1 with additional adjustment for pre birth confounders (family history of depression, maternal education).
Model 3: as model 2 with additional adjustment for childhood confounders (borderline personality, IQ at age 8, depression at age 12, conduct disorder trajectory group membership, peer problems, bullied).
Model 4a: as model 3 with additional adjustment for cannabis use.
Model 4b: as model 3 with additional adjustment for alcohol use.
Model 4c: as model 3 with additional adjustment for illicit drug use (other than cannabis).
Model 5: as model 3 with additional adjustment for cannabis, alcohol and other illicit drug use.